Patanjali Yoga Sutra — ततः कृतार्थानां परिणामक्रमसमाप्तिर्गुणानाम् ॥4.32॥

tataḥ kṛtārthānāṁ pariṇāmakramasamāptirguṇānām॥

Then such a yogi transcends the influences of triguṇas as their purpose is attained and transformation or mutation is just a thing of the past for him.

The three Guṇas ‘cause’ the mutation (= effect) in prakṛti. In sūtra 4.2, we have understood that mutation from one species into another evolved species is caused by prakṛti. And in sūtra 2.18, the understanding is that the Puruṣa experiences prakṛti and the guṇas, being evolutes of prakṛti, influence such an experience. On having Guṇas accomplished their purpose, there is nothing left to the guṇas to be done, and thus the Puruṣa finally gets liberation. Once the yogi has gone beyond the triguṇas (due to dharmamegha samādhi), what influence, the ‘effect’ will have on him?

In the words of Bhagavān such a Yogi is ‘triguṇātīta’ who displays certain profound conduct:

मानापमानयोस्तुल्यस्तुल्यो मित्रारिपक्षयोः।

सर्वारम्भपरित्यागी गुणातीतः स उच्यते॥१४.२५॥

mānāpamānayostulyastulyo mitrāripakṣayoḥ।

sarvārambhaparityāgī guṇātītaḥ sa ucyate॥Gītā 14.25॥

A person is said to have transcended the guṇās, when honor and humiliation are viewed equally by him, when foe and friend are alike to him.